Amlodipine Drug Interactions

CCBs have key interactions especially with other cardiac drugs and CYP3A4-affecting agents.

Key Drug Interactions

→Beta blockers with verapamil/diltiazem: risk of complete heart block
→Digoxin: verapamil and diltiazem increase digoxin levels
→CYP3A4 inhibitors (azoles, macrolides): increase CCB levels
→Statins (simvastatin, lovastatin): amlodipine increases statin levels
→Ciclosporin: CCBs increase levels

Alcohol Interactions

→Alcohol can enhance blood pressure-lowering effects, increasing dizziness risk.

Supplement and Food Interactions

→Avoid grapefruit and grapefruit juice with dihydropyridine CCBs and diltiazem. St John's Wort reduces CCB efficacy.

Safety Note

Always tell your doctor and pharmacist about all prescription medicines, non-prescription medicines, vitamins, and herbal or dietary supplements before starting Amlodipine. Keep an up-to-date medicines list to share with all healthcare providers.

Frequently Asked Questions

Can I take Amlodipine with common over-the-counter medicines?

Some OTC medications interact with Amlodipine. NSAIDs, aspirin, antihistamines, antacids, and herbal products can all have interactions. Ask your pharmacist to check for interactions before taking any new OTC product.

Can I drink alcohol while taking Amlodipine?

Alcohol can enhance blood pressure-lowering effects, increasing dizziness risk.

More About Amlodipine

Dosage & Administration

Side Effects

Warnings & Precautions

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Medical Disclaimer: This drug reference is provided for informational purposes only and is not a substitute for professional medical advice. Always consult your physician or pharmacist before changing your medication. Information reviewed by the vHospital Editorial Team · Sources: WHO, BNF, FDA prescribing information.