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ACE InhibitorPrescription Only

Ramipril Drug Interactions

ACE inhibitors interact with agents that affect potassium, renal function, and blood pressure.

Key Drug Interactions

  • Potassium-sparing diuretics / potassium supplements: risk of hyperkalaemia
  • NSAIDs: reduced antihypertensive effect; increased nephrotoxicity
  • ARBs: dual RAS blockade increases risk of hyperkalaemia and kidney injury
  • Aliskiren: contraindicated in diabetes or renal impairment
  • Lithium: ACE inhibitors can increase lithium levels
  • Antidiabetics: may enhance hypoglycaemic effect

Alcohol Interactions

  • Alcohol can enhance blood pressure-lowering effect, increasing risk of dizziness and fainting. Limit alcohol intake.

Supplement and Food Interactions

  • Potassium supplements and potassium-containing salt substitutes should be avoided or monitored carefully.

Safety Note

Always tell your doctor and pharmacist about all prescription medicines, non-prescription medicines, vitamins, and herbal or dietary supplements before starting Ramipril. Keep an up-to-date medicines list to share with all healthcare providers.

Frequently Asked Questions

Can I take Ramipril with common over-the-counter medicines?

Some OTC medications interact with Ramipril. NSAIDs, aspirin, antihistamines, antacids, and herbal products can all have interactions. Ask your pharmacist to check for interactions before taking any new OTC product.

Can I drink alcohol while taking Ramipril?

Alcohol can enhance blood pressure-lowering effect, increasing risk of dizziness and fainting. Limit alcohol intake.

More About Ramipril

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Medical Disclaimer: This drug reference is provided for informational purposes only and is not a substitute for professional medical advice. Always consult your physician or pharmacist before changing your medication. Information reviewed by the vHospital Editorial Team · Sources: WHO, BNF, FDA prescribing information.