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VHOSPITAL.CLINIC · Drug Reference

Proton Pump InhibitorAvailable OTC

Rabeprazole Side Effects

Like all medications, Rabeprazole can cause side effects. Most people do not experience serious adverse effects, but it is important to know what to look for and when to seek medical care.

Common Side Effects

  • Headache
  • Diarrhoea or constipation
  • Nausea and abdominal pain
  • Flatulence

Serious Side Effects

  • Hypomagnesaemia with long-term use
  • C. difficile infection (increased risk)
  • Bone fracture risk with prolonged high-dose use
  • Acute interstitial nephritis (rare)
  • Hyponatraemia

When to Seek Medical Care

  • Muscle cramps, tremors, or seizures (low magnesium)
  • Severe diarrhoea
  • Blood in stool
  • Significant unintended weight loss

Safety Note

If you experience any unexpected or concerning symptoms while taking Rabeprazole, contact your doctor or pharmacist. Do not stop taking Rabeprazole without medical advice unless you experience a serious adverse reaction.

Frequently Asked Questions

Are side effects from Rabeprazole common?

Most patients tolerate Rabeprazole well at therapeutic doses. Common side effects are usually mild and often improve after the first few weeks. Serious side effects are less common but should be reported immediately.

What should I do if I experience side effects from Rabeprazole?

Mild side effects: discuss with your pharmacist, as many resolve spontaneously. Serious side effects: seek medical care immediately and contact your prescriber. Do not stop Rabeprazole abruptly for long-term conditions without medical advice.

More About Rabeprazole

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Medical Disclaimer: This drug reference is provided for informational purposes only and is not a substitute for professional medical advice. Always consult your physician or pharmacist before changing your medication. Information reviewed by the vHospital Editorial Team · Sources: WHO, BNF, FDA prescribing information.