Losartan Warnings & Precautions

Before taking Losartan, inform your doctor of all your medical conditions and medications. Certain conditions and patient groups require special precautions or may make Losartan unsuitable.

Key Warnings

→Contraindicated in pregnancy
→Monitor renal function and potassium regularly
→Do not combine with ACE inhibitor without specialist supervision

Pregnancy and Breastfeeding

→Absolutely contraindicated in pregnancy. Causes fetal renal toxicity, oligohydramnios, and can be fatal to the fetus. Discontinue and switch immediately if pregnancy occurs.

Older Adults

→Start at low doses to avoid excessive blood pressure lowering and falls. Monitor renal function and potassium closely.

Chronic Conditions

→In CKD with proteinuria: highly beneficial but requires close monitoring. Avoid in bilateral renal artery stenosis.

When Not to Use

→Pregnancy
→Concurrent ACE inhibitor and aliskiren (in diabetes/CKD)
→History of angioedema with any ARB or ACE inhibitor

Safety Note

Losartan should only be taken as prescribed. If you have any concerns about whether Losartan is suitable for you, consult your doctor or pharmacist.

Frequently Asked Questions

Is Losartan safe for everyone?

Losartan is not suitable for everyone. Contraindicated in pregnancy Always inform your doctor of all medical conditions before starting Losartan.

What is the difference between an ACE inhibitor and an ARB?

Both block the renin-angiotensin system but at different points. ACE inhibitors prevent angiotensin II formation; ARBs block its receptor. ARBs do not cause the cough associated with ACE inhibitors, making them a preferred alternative in patients who cannot tolerate ACE inhibitor-induced cough.

More About Losartan

Dosage & Administration

Side Effects

Drug Interactions

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Medical Disclaimer: This drug reference is provided for informational purposes only and is not a substitute for professional medical advice. Always consult your physician or pharmacist before changing your medication. Information reviewed by the vHospital Editorial Team · Sources: WHO, BNF, FDA prescribing information.