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VHOSPITAL.CLINIC · Drug Reference

HIV Integrase InhibitorPrescription Only

Elvitegravir Drug Interactions

Antiviral interactions vary significantly by drug class.

Key Drug Interactions

  • HIV antivirals have numerous drug interactions — specialist prescribing required
  • Nephrotoxic drugs combined with acyclovir/tenofovir: increased renal risk
  • Immunosuppressants: overlapping toxicity with ganciclovir

Alcohol Interactions

  • Alcohol is not specifically contraindicated with most antivirals but may worsen underlying liver disease (important in hepatitis treatment).

Supplement and Food Interactions

  • St John's Wort significantly reduces levels of many antivirals (especially HIV drugs) — absolutely contraindicated with HIV antivirals.

Safety Note

Always tell your doctor and pharmacist about all prescription medicines, non-prescription medicines, vitamins, and herbal or dietary supplements before starting Elvitegravir. Keep an up-to-date medicines list to share with all healthcare providers.

Frequently Asked Questions

Can I take Elvitegravir with common over-the-counter medicines?

Some OTC medications interact with Elvitegravir. NSAIDs, aspirin, antihistamines, antacids, and herbal products can all have interactions. Ask your pharmacist to check for interactions before taking any new OTC product.

Can I drink alcohol while taking Elvitegravir?

Alcohol is not specifically contraindicated with most antivirals but may worsen underlying liver disease (important in hepatitis treatment).

More About Elvitegravir

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Medical Disclaimer: This drug reference is provided for informational purposes only and is not a substitute for professional medical advice. Always consult your physician or pharmacist before changing your medication. Information reviewed by the vHospital Editorial Team · Sources: WHO, BNF, FDA prescribing information.