VHOSPITAL.CLINIC · Drug Reference

NSAIDAvailable OTC

Diflunisal Side Effects

Like all medications, Diflunisal can cause side effects. Most people do not experience serious adverse effects, but it is important to know what to look for and when to seek medical care.

Common Side Effects

  • Stomach upset, nausea, or heartburn
  • Dizziness or headache
  • Fluid retention or mild oedema
  • Indigestion or bloating

Serious Side Effects

  • Gastrointestinal bleeding or peptic ulcer
  • Acute kidney injury with prolonged use
  • Cardiovascular events (heart attack, stroke) with long-term use
  • Severe allergic reaction or skin reactions
  • Liver toxicity (rare)

When to Seek Medical Care

  • Black, tarry, or bloody stools
  • Sudden severe abdominal pain
  • Chest pain or shortness of breath during use
  • Swelling of the face, lips, or throat
  • Significant decrease in urine output

Safety Note

If you experience any unexpected or concerning symptoms while taking Diflunisal, contact your doctor or pharmacist. Do not stop taking Diflunisal without medical advice unless you experience a serious adverse reaction.

Frequently Asked Questions

Are side effects from Diflunisal common?

Most patients tolerate Diflunisal well at therapeutic doses. Common side effects are usually mild and often improve after the first few weeks. Serious side effects are less common but should be reported immediately.

What should I do if I experience side effects from Diflunisal?

Mild side effects: discuss with your pharmacist, as many resolve spontaneously. Serious side effects: seek medical care immediately and contact your prescriber. Do not stop Diflunisal abruptly for long-term conditions without medical advice.

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Medical Disclaimer: This drug reference is provided for informational purposes only and is not a substitute for professional medical advice. Always consult your physician or pharmacist before changing your medication. Information reviewed by the vHospital Editorial Team · Sources: WHO, BNF, FDA prescribing information.