VHOSPITAL.CLINIC · Drug Reference

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Aripiprazole Side Effects

Like all medications, Aripiprazole can cause side effects. Most people do not experience serious adverse effects, but it is important to know what to look for and when to seek medical care.

Common Side Effects

  • Sedation and drowsiness
  • Weight gain (especially atypicals: olanzapine, quetiapine, clozapine)
  • Metabolic syndrome (diabetes, dyslipidaemia)
  • Extrapyramidal symptoms (typical antipsychotics: tremor, rigidity, restlessness)

Serious Side Effects

  • Tardive dyskinesia (irreversible involuntary movements with long-term use)
  • Neuroleptic malignant syndrome (rare but life-threatening: hyperthermia, rigidity, altered consciousness)
  • QT prolongation
  • Agranulocytosis (clozapine)
  • Hyperprolactinaemia

When to Seek Medical Care

  • High fever with muscle rigidity and confusion (NMS — medical emergency)
  • Involuntary facial or limb movements
  • Severe restlessness
  • Fainting or palpitations

Safety Note

If you experience any unexpected or concerning symptoms while taking Aripiprazole, contact your doctor or pharmacist. Do not stop taking Aripiprazole without medical advice unless you experience a serious adverse reaction.

Frequently Asked Questions

Are side effects from Aripiprazole common?

Most patients tolerate Aripiprazole well at therapeutic doses. Common side effects are usually mild and often improve after the first few weeks. Serious side effects are less common but should be reported immediately.

What should I do if I experience side effects from Aripiprazole?

Mild side effects: discuss with your pharmacist, as many resolve spontaneously. Serious side effects: seek medical care immediately and contact your prescriber. Do not stop Aripiprazole abruptly for long-term conditions without medical advice.

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Medical Disclaimer: This drug reference is provided for informational purposes only and is not a substitute for professional medical advice. Always consult your physician or pharmacist before changing your medication. Information reviewed by the vHospital Editorial Team · Sources: WHO, BNF, FDA prescribing information.