Palpitations: Clinical Meaning

Hypertension

Hypertension (high blood pressure) is a condition where the force of blood against artery walls is consistently too high. Often called the 'silent killer', it usually has no symptoms but significantly increases the risk of heart attack, stroke, and kidney disease.

Hyperthyroidism

Hyperthyroidism occurs when the thyroid gland produces too much thyroid hormone, speeding up metabolism. It causes weight loss, rapid heartbeat, anxiety, tremors, and heat intolerance. Graves' disease is the most common cause.

Anxiety Disorder

Anxiety disorders are among the most common mental health conditions, characterized by excessive fear, worry, or nervousness that interferes with daily activities. Types include generalized anxiety disorder (GAD), panic disorder, and social anxiety.

Heart Attack (Myocardial Infarction)

A heart attack occurs when blood flow to part of the heart muscle is blocked, usually by a blood clot in a coronary artery. Immediate treatment is critical. Symptoms include chest pain, pressure radiating to the arm or jaw, sweating, and nausea.

Heart Failure

Heart failure occurs when the heart cannot pump enough blood to meet the body's needs. It is a chronic condition that causes fatigue, shortness of breath, and fluid retention (edema). It requires ongoing medical management.

Cardiac Arrhythmia

Cardiac arrhythmia refers to irregular heart rhythms — the heart beats too fast, too slow, or with an irregular pattern. Some arrhythmias are harmless, while others (like atrial fibrillation) significantly increase the risk of stroke and heart failure.

Aortic Stenosis

Aortic stenosis is narrowing of the aortic valve opening, restricting blood flow from the heart. It causes exertional chest pain, syncope, and heart failure; valve replacement is required for severe symptomatic disease.

Mitral Valve Disease

Mitral valve disease includes mitral regurgitation (valve leaking) and mitral stenosis (valve narrowing), causing symptoms of breathlessness, fatigue, and palpitations. Rheumatic heart disease is a major cause worldwide.

Myocarditis

Myocarditis is inflammation of the heart muscle, most commonly caused by viral infections (particularly enteroviruses). It can present with chest pain, shortness of breath, palpitations, and in severe cases, heart failure or sudden death.

Pericarditis

Pericarditis is inflammation of the pericardium (the sac surrounding the heart), causing sharp, pleuritic chest pain that improves when leaning forward. Viral infections are the most common cause; NSAIDs are the primary treatment.

Cardiomyopathy

Cardiomyopathy is disease of the heart muscle that impairs its ability to pump blood effectively. Types include dilated (most common), hypertrophic, and restrictive; causes range from genetic mutations to chronic alcohol use.

Cushing's Syndrome

Cushing's syndrome results from prolonged exposure to high cortisol levels, causing central obesity, moon face, buffalo hump, skin thinning, and hypertension. The most common cause is exogenous corticosteroid use; endogenous causes include pituitary or adrenal tumors.

Metabolic Syndrome

Metabolic syndrome is a cluster of conditions (abdominal obesity, hypertension, hyperglycemia, low HDL cholesterol, high triglycerides) that together significantly increase cardiovascular and diabetes risk. Lifestyle modification is the cornerstone of management.

Iron Deficiency Anemia

Iron deficiency anemia is the most common nutritional deficiency worldwide, caused by inadequate dietary intake, blood loss, or malabsorption. It causes fatigue, pallor, shortness of breath, and pica; iron supplementation is the treatment.

Pulmonary Hypertension

Pulmonary hypertension is elevated pressure in the pulmonary arteries, causing progressive exertional dyspnea, syncope, and right heart failure. It is classified into five groups based on etiology; targeted therapies improve outcomes in pulmonary arterial hypertension.

Chronic Kidney Disease (CKD)

CKD is progressive, irreversible loss of kidney function over months to years, classified in stages 1-5 based on GFR. Diabetes and hypertension are the leading causes; management focuses on slowing progression and managing complications.

Glomerulonephritis

Glomerulonephritis is inflammation of the glomeruli causing hematuria, proteinuria, hypertension, and impaired kidney function. It can be acute (post-streptococcal) or chronic; IgA nephropathy is the most common form worldwide.

Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease is the most common hereditary kidney disorder, causing progressive enlargement of fluid-filled cysts in the kidneys, hypertension, and eventual kidney failure. Tolvaptan slows kidney growth.

Renal Artery Stenosis

Renal artery stenosis is narrowing of the arteries supplying the kidneys, causing renovascular hypertension that is resistant to standard treatment and can lead to ischemic nephropathy. Atherosclerosis and fibromuscular dysplasia are the main causes.

Preeclampsia

Preeclampsia is a pregnancy complication characterized by hypertension and proteinuria after 20 weeks gestation, potentially progressing to eclampsia (seizures) and multi-organ failure. Delivery is the definitive treatment; low-dose aspirin is preventive in high-risk women.

Atrial Fibrillation

Atrial fibrillation (AFib) is the most common cardiac arrhythmia, characterized by rapid and irregular atrial beating. It significantly increases stroke and heart failure risk.

Panic Disorder

Panic disorder is characterized by recurrent unexpected panic attacks with intense physical symptoms. It often leads to persistent worry about future attacks and behavioral avoidance.

Hypoglycemia

Hypoglycemia is low blood sugar, typically below 70 mg/dL. Most common in people with diabetes, it causes rapid neurological and adrenaline-driven symptoms requiring prompt treatment.

Anemia

Anemia is a condition where there are insufficient healthy red blood cells to carry adequate oxygen to body tissues. It has many causes including nutritional deficiencies, chronic disease, and blood loss.

Pulmonary Arterial Hypertension

Pulmonary arterial hypertension is high blood pressure in the arteries supplying the lungs. It causes the right side of the heart to work harder, eventually leading to heart failure.

Myocarditis

Myocarditis is inflammation of the heart muscle, most commonly caused by viral infections. It can affect the heart's electrical system and pumping ability, ranging from mild to life-threatening.