Hair Loss: Clinical Meaning

Hypothyroidism

Hypothyroidism occurs when the thyroid gland doesn't produce enough thyroid hormone. This slows metabolism and causes fatigue, weight gain, cold intolerance, constipation, and depression. Hashimoto's thyroiditis is the most common cause.

Hyperthyroidism

Hyperthyroidism occurs when the thyroid gland produces too much thyroid hormone, speeding up metabolism. It causes weight loss, rapid heartbeat, anxiety, tremors, and heat intolerance. Graves' disease is the most common cause.

PCOS (Polycystic Ovary Syndrome)

Polycystic ovary syndrome (PCOS) is a hormonal disorder common among women of reproductive age, causing irregular periods, excess androgen levels, and polycystic ovaries. It is associated with insulin resistance and increased risk of diabetes and heart disease.

Systemic Lupus Erythematosus (SLE)

SLE is a chronic autoimmune disease that can affect multiple organ systems including the skin, joints, kidneys, and nervous system. The characteristic butterfly rash, joint pain, and kidney disease are hallmarks; flares are managed with immunosuppressants.

Anorexia Nervosa

Anorexia nervosa is an eating disorder with severe food restriction, intense fear of weight gain, and distorted body image. It has the highest mortality rate of any psychiatric disorder; multidisciplinary treatment including nutritional rehabilitation and psychotherapy is essential.

Alopecia Areata

Alopecia areata is an autoimmune condition causing patchy hair loss when the immune system attacks hair follicles. It can progress to total scalp (alopecia totalis) or body hair loss (alopecia universalis); intralesional corticosteroids and JAK inhibitors are effective.

Seborrheic Dermatitis

Seborrheic dermatitis is a chronic inflammatory skin condition causing scaly patches and red skin, particularly on the scalp (dandruff), face, and chest. Malassezia yeast overgrowth plays a role; antifungal shampoos and mild topical steroids are effective.

Zinc Deficiency

Zinc deficiency affects approximately 2 billion people worldwide, impacting immunity, wound healing, protein synthesis, and taste and smell.

Iodine Deficiency

Iodine deficiency is the leading preventable cause of intellectual disability worldwide. The thyroid requires iodine to produce hormones; deficiency leads to hypothyroidism and goiter.