Constipation: Clinical Meaning

Hypothyroidism

Hypothyroidism occurs when the thyroid gland doesn't produce enough thyroid hormone. This slows metabolism and causes fatigue, weight gain, cold intolerance, constipation, and depression. Hashimoto's thyroiditis is the most common cause.

Parkinson's Disease

Parkinson's disease is a progressive neurological disorder affecting movement, caused by the loss of dopamine-producing neurons. Symptoms include tremor, rigidity, slowness of movement, and balance problems. There is no cure, but treatments can manage symptoms.

Colorectal Cancer

Colorectal cancer develops in the colon or rectum and is the third most common cancer globally. Risk factors include age over 50, family history, inflammatory bowel disease, and diet high in red/processed meat.

Irritable Bowel Syndrome (IBS)

IBS is a functional gastrointestinal disorder causing recurrent abdominal pain related to defecation, with altered stool frequency or consistency. It affects up to 15% of the population; dietary changes, stress management, and symptom-specific medications help.

Diverticulitis

Diverticulitis occurs when diverticula (small pouches in the colon wall) become inflamed or infected, causing left lower quadrant pain, fever, and bowel changes. Uncomplicated cases are treated with antibiotics; perforation or abscess may require surgery.

Hemorrhoids

Hemorrhoids are swollen veins in the rectum or anus causing rectal bleeding, itching, and discomfort. They are classified as internal (above the dentate line) or external; most respond to dietary changes and topical treatments.

Anal Fissure

An anal fissure is a small tear in the lining of the anal canal causing sharp pain and bleeding during bowel movements. Chronic fissures may require topical nitroglycerin, calcium channel blockers, or surgical treatment.

Intestinal Obstruction

Intestinal obstruction is blockage of the small or large bowel, causing abdominal pain, distension, vomiting, and inability to pass gas or stool. Adhesions and hernias are the most common causes; emergency surgery may be required.

Colon Polyps

Colon polyps are growths on the inner lining of the colon that are usually asymptomatic but can develop into colorectal cancer over time. Colonoscopy is the gold standard for detection and polypectomy; surveillance intervals depend on polyp type and size.

Magnesium Deficiency

Magnesium deficiency affects an estimated 10-30% of the population. Magnesium is involved in over 300 enzymatic reactions in the body, making deficiency wide-ranging in effects.

Iodine Deficiency

Iodine deficiency is the leading preventable cause of intellectual disability worldwide. The thyroid requires iodine to produce hormones; deficiency leads to hypothyroidism and goiter.

Hypercalcemia

Hypercalcemia is elevated blood calcium, most commonly caused by overactive parathyroid glands or cancer. Symptoms follow the mnemonic 'bones, stones, groans, and psychic moans'.

Diverticulitis

Diverticulitis occurs when small pouches (diverticula) that form in the digestive tract become inflamed or infected. It causes abdominal pain and can lead to serious complications.