How Is Whooping Cough (Pertussis) Diagnosed? Tests, Criteria & Process
Whooping Cough (Pertussis) diagnosis relies on Full blood count (FBC), Comprehensive metabolic panel (electrolytes, creatinine, LFTs), Urinalysis. Learn the full diagnostic pathway, clinical criteria, differential workup, and what to expect at your evaluation.
Updated March 27, 2026
Whooping Cough (Pertussis) is diagnosed using Full blood count (FBC), Comprehensive metabolic panel (electrolytes, creatinine, LFTs), Urinalysis and targeted clinical evaluation. Whooping cough is a highly contagious bacterial respiratory infection caused by Bordetella pertussis. It causes severe coughing fits followed by a high-pitched 'whoop' sound during breathing. It is most dangerous in infants. DTaP vaccination provides protection.
Clinical Context
The diagnostic process for Whooping Cough (Pertussis) begins with Thorough history and physical examination followed by basic blood and urine tests; targeted specialist investigation as needed. Key investigations include Full blood count (FBC), Comprehensive metabolic panel (electrolytes, creatinine, LFTs), Urinalysis, Chest X-ray. The gold standard is: Directed investigation based on clinical history and physical examination findings. Clinical guidelines from NICE / BMJ Best Practice / WHO define the diagnostic criteria and recommended investigation pathway.
Clinical Pathway
Whooping Cough (Pertussis) — Full Condition GuideCondition HubWhooping Cough (Pertussis) — Differential DiagnosisDifferentialWhooping Cough (Pertussis) — Treatment PathwaysTreatmentWhooping Cough (Pertussis) — Prognosis & OutlookPrognosisFrequently Asked Questions
How Is Whooping Cough (Pertussis) Diagnosed? Tests, Criteria & Process?+
Whooping Cough (Pertussis) is diagnosed using Full blood count (FBC), Comprehensive metabolic panel (electrolytes, creatinine, LFTs), Urinalysis and targeted clinical evaluation. Whooping cough is a highly contagious bacterial respiratory infection caused by Bordetella pertussis. It causes severe coughing fits followed by a high-pitched 'whoop' sound during breathing. It is most dangerous in infants. DTaP vaccination provides protection.
How do doctors test for whooping cough (pertussis)?+
The main tests used to diagnose Whooping Cough (Pertussis) include Full blood count (FBC), Comprehensive metabolic panel (electrolytes, creatinine, LFTs), Urinalysis. Your doctor will select investigations based on your symptoms, clinical findings, and risk factors.
How long does it take to diagnose Whooping Cough (Pertussis)?+
The time to diagnosis varies. Some cases are identified within hours using clinical presentation and blood tests; others require weeks, repeated investigations, or specialist referral.
Can Whooping Cough (Pertussis) be missed on initial testing?+
Yes — Whooping Cough (Pertussis) can be missed if initial tests are negative or if the presentation is atypical. If clinical suspicion remains high, repeat testing or specialist referral is appropriate.
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