VHOSPITAL.CLINIC · Health Guide

Gallstones: Causes, Symptoms and Treatment

Understanding gallstones, what symptoms they cause, and when surgery is needed.

Gallstones are hardened deposits of bile that form in the gallbladder. They affect 10-15% of adults and are the most common cause of upper abdominal pain requiring surgery.

Risk factors include female sex, obesity, rapid weight loss, diabetes, and family history. Most gallstones remain silent; symptoms occur when a stone blocks the bile duct.

Symptomatic gallstones cause biliary colic: severe right upper abdominal pain, often triggered by fatty meals. Complications include cholecystitis, cholangitis, and pancreatitis.

Cholecystectomy (gallbladder removal) is the definitive treatment. The laparoscopic approach allows most patients to go home the same day.

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Possible Causes

  • Infections and inflammation — bacterial, viral, or autoimmune triggers activate nausea
  • Metabolic disturbances — hormonal imbalances, nutrient deficiencies, or blood sugar changes
  • Structural or vascular causes — tissue damage, nerve compression, or circulatory problems
  • Psychological factors — stress, anxiety, and depression can produce measurable physical nausea

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Medical ReviewvHospital Editorial Team · 2024–2025
Sources:WHOPubMedUpToDateNICE