VHOSPITAL.CLINIC · Drug Reference
Sertraline is a selective serotonin reuptake inhibitor (SSRI) used as a first-line treatment for depression, anxiety disorders, OCD, and PTSD.
SSRIs (Selective Serotonin Reuptake Inhibitors) block the reuptake of serotonin into presynaptic neurons, increasing serotonin availability in the synaptic cleft. They are the first-line pharmacological treatment for depression and anxiety disorders.
First-line treatment for depression, generalised anxiety disorder, panic disorder, OCD, PTSD, social anxiety disorder, and premenstrual dysphoric disorder.
Full antidepressant effect takes 4–6 weeks. Do not stop abruptly. Monitor for increased suicidal ideation especially in early treatment in young adults.
Fluoxetine
Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) used as a first-line treatment for depression, anxiety disorders, OCD, and PTSD.
Paroxetine
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) used as a first-line treatment for depression, anxiety disorders, OCD, and PTSD.
Citalopram
Citalopram is a selective serotonin reuptake inhibitor (SSRI) used as a first-line treatment for depression, anxiety disorders, OCD, and PTSD.
Escitalopram
Escitalopram is a selective serotonin reuptake inhibitor (SSRI) used as a first-line treatment for depression, anxiety disorders, OCD, and PTSD.
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Start Free AI Analysis →Medical Disclaimer: This drug reference is provided for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider before starting, stopping, or changing any medication. Information reviewed by the vHospital Editorial Team · Sources: WHO, BNF, FDA prescribing information, UpToDate.