VHOSPITAL.CLINIC · Drug Reference

ACE InhibitorPrescription Only

Perindopril

Perindopril is an ACE inhibitor that lowers blood pressure, reduces cardiac workload, and provides kidney protection in hypertension, heart failure, and diabetic nephropathy.

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Clinical Data

Overview

ACE inhibitors block angiotensin-converting enzyme, preventing formation of angiotensin II. This causes vasodilation, reduces aldosterone secretion, and lowers blood pressure. They also have cardioprotective and nephroprotective effects.

What Perindopril Is Used For

First-line treatment for hypertension, heart failure, post-myocardial infarction, diabetic nephropathy, and chronic kidney disease. Also used to reduce cardiovascular risk in high-risk patients.

Safety Summary

Monitor blood pressure, renal function, and potassium after initiation and dose changes. Persistent dry cough is the most common reason for discontinuation.

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Medical Disclaimer: This drug reference is provided for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider before starting, stopping, or changing any medication. Information reviewed by the vHospital Editorial Team · Sources: WHO, BNF, FDA prescribing information, UpToDate.