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Calcium Channel BlockerPrescription Only

Nicardipine

Nicardipine is a calcium channel blocker that relaxes blood vessels and reduces cardiac workload, used to treat hypertension, angina, and certain arrhythmias.

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Overview

Calcium channel blockers (CCBs) prevent calcium ions from entering vascular smooth muscle and cardiac cells, causing vasodilation and, for some agents, reducing heart rate and contractility.

What Nicardipine Is Used For

Dihydropyridine CCBs (amlodipine, nifedipine) are used mainly for hypertension and angina. Non-dihydropyridine CCBs (diltiazem, verapamil) also slow heart rate and are used for atrial fibrillation and SVT.

Safety Summary

Ankle swelling is common with dihydropyridines. Non-dihydropyridines must not be combined with beta blockers due to heart block risk.

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Medical Disclaimer: This drug reference is provided for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider before starting, stopping, or changing any medication. Information reviewed by the vHospital Editorial Team · Sources: WHO, BNF, FDA prescribing information, UpToDate.