VHOSPITAL.CLINIC · Drug Reference
Methylnaltrexone is an opioid antagonist used to reverse opioid overdose or treat opioid and alcohol dependence.
Opioid analgesics act on opioid receptors in the brain and spinal cord to reduce the perception of pain. They are effective for moderate to severe pain but carry risks of dependence, tolerance, and respiratory depression.
Used for moderate to severe pain where non-opioid analgesics are insufficient, including post-surgical pain, cancer pain, and severe acute injuries.
Use the lowest effective dose for the shortest duration. Never exceed prescribed doses. Keep out of reach of others. Do not stop abruptly after prolonged use.
Describe your symptoms and concerns and get a structured clinical assessment — possible causes, red flags, and recommended next steps.
Start Free AI Analysis →Medical Disclaimer: This drug reference is provided for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider before starting, stopping, or changing any medication. Information reviewed by the vHospital Editorial Team · Sources: WHO, BNF, FDA prescribing information, UpToDate.