VHOSPITAL.CLINIC · Drug Reference
Esomeprazole is a proton pump inhibitor (PPI) that reduces gastric acid production and is used to treat acid reflux, GERD, and peptic ulcers.
PPIs irreversibly inhibit the gastric proton pump (H⁺/K⁺-ATPase), the final step in gastric acid secretion. They provide the most potent acid suppression available and are among the most prescribed drug classes globally.
Used for gastroesophageal reflux disease (GERD), peptic ulcer disease, H. pylori eradication (as part of triple therapy), Zollinger-Ellison syndrome, and prevention of NSAID-related ulcers.
Take 30–60 minutes before the first meal of the day for optimal efficacy. Avoid long-term use without reassessment. Short-term use at the lowest effective dose is preferred.
Omeprazole
Omeprazole is a proton pump inhibitor (PPI) that reduces gastric acid production and is used to treat acid reflux, GERD, and peptic ulcers.
Pantoprazole
Pantoprazole is a proton pump inhibitor (PPI) that reduces gastric acid production and is used to treat acid reflux, GERD, and peptic ulcers.
Lansoprazole
Lansoprazole is a proton pump inhibitor (PPI) that reduces gastric acid production and is used to treat acid reflux, GERD, and peptic ulcers.
Rabeprazole
Rabeprazole is a proton pump inhibitor (PPI) that reduces gastric acid production and is used to treat acid reflux, GERD, and peptic ulcers.
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Start Free AI Analysis →Medical Disclaimer: This drug reference is provided for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider before starting, stopping, or changing any medication. Information reviewed by the vHospital Editorial Team · Sources: WHO, BNF, FDA prescribing information, UpToDate.