VHOSPITAL.CLINIC · Parasite Treatment Drug
Albendazole 400 mg as a single dose is an effective alternative to mebendazole for pinworm infection, with comparable efficacy and the same repeat-dosing strategy.
Albendazole is rapidly converted in the body to its active sulphoxide metabolite, which inhibits β-tubulin polymerisation in Enterobius, disrupting glucose uptake and killing the worm.
Single dose of 400 mg, repeated at 2 weeks. Albendazole is better absorbed with fatty food (though minimal systemic effect is needed for intestinal worms). Treat all household contacts.
This is a general reference. Always follow your physician's prescription and local treatment guidelines.
Both are equally effective in clinical trials. Albendazole 400 mg single dose and mebendazole 100 mg single dose achieve similar cure rates (>90%). The choice depends on availability and local guidelines.
Wash all bedding, towels, and clothing on the day of treatment. Shower each morning (eggs are deposited overnight). Trim fingernails. These measures prevent reinfection while medication acts.
Albendazole is generally recommended for children aged 2 years and above. For children under 2, paediatric dosing guidance should be followed, and mebendazole is often preferred.
Albendazole treats Enterobiasis (Pinworm Infection), which can cause these symptoms:
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