BPH is non-malignant enlargement of the prostate gland causing lower urinary tract symptoms including weak stream, frequency, urgency, and nocturia. It is nearly universal in men over 80; alpha-blockers and 5-alpha reductase inhibitors are first-line treatments.
Doxazosin is an alpha-1 blocker used to treat hypertension and benign prostatic hyperplasia by relaxing smooth muscle in blood vessels and the prostate.
Prazosin is an alpha-1 blocker used to treat hypertension and benign prostatic hyperplasia by relaxing smooth muscle in blood vessels and the prostate.
Terazosin is an alpha-1 blocker used to treat hypertension and benign prostatic hyperplasia by relaxing smooth muscle in blood vessels and the prostate.
Tamsulosin is an alpha-1 blocker that relaxes smooth muscle in the prostate and bladder neck to improve urinary flow in benign prostatic hyperplasia.
Alfuzosin is an alpha-1 blocker that relaxes smooth muscle in the prostate and bladder neck to improve urinary flow in benign prostatic hyperplasia.
Finasteride is a 5-alpha reductase inhibitor that shrinks the prostate in BPH and reduces hair loss in androgenic alopecia.
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